S44 Recent Developments in Norovirus Research

Wednesday, August 6, 2014: 1:30 PM-3:30 PM
Wabash 2-3 (Indiana Convention Center)
Primary Contact: Stephen Grove
Organizers: David Kingsley and Stephen Grove
Convenors: Stephen Grove and David Kingsley
Human norovirus is now recognized as the major cause of foodborne illness in many parts of the world.  While substantial research has been performed using surrogate viruses, it is increasingly clear that the utility of surrogates for answering key questions about human norovirus is limited.  Currently many basic questions about human norovirus are largely unknown since the virus cannot be replicated in the laboratory.

In this symposium proposal, we intend to present forward-looking research on norovirus, which will be critical in our ability to control spread the pathogen.  For example, research on in vitro replication of human norovirus focusing on stems cells appears promising; could this be a long-awaited break through?  One way to determine infectivity of human norovirus is through human volunteers trials; how feasible and safe are they?  Research into norovirus vaccine development is progressing; will it someday be possible to vaccinate against norovirus?

The focus on state of the art research will provide the audience a rounded understanding of the challenges faced by researchers, as well as the promising avenues that are being explored to address the public health concern around human norovirus.

Presentations

2:30 PM
Progress in NoV Volunteer Studies
Juan Leon, Emory University
3:00 PM
Progress in Norovirus Vaccine Development
Melissa Herbst-Kralovetz, University of Arizona
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