P3-51 The Effect of Pesticides on the Growth and Survival of Foodborne Human Pathogens

Wednesday, July 25, 2012
Exhibit Hall (Rhode Island Convention Center)
Shefali Dobhal, Oklahoma State University, Stillwater, OK
Guodong Zhang, U.S. Food and Drug Administration, College Park, MD
Tom Royer, Oklahoma State University, Stillwater, OK
John Damicone, Oklahoma State University, Stillwater, OK
Li Ma, Oklahoma State University, Stillwater, OK
Introduction: Pesticides are widely used to control pests in the field production of fresh fruits and vegetables.  Depending on the interaction between pesticides and human pathogens, pesticide sprays on fresh produce could be a source of contamination of human pathogens or an additional control for such contamination. 

Purpose: The aim of this study was to evaluate the effect of pesticides on the growth and survival of the foodborne human pathogens E. coli O157:H7 and Salmonella Typhimurium.

Methods: Eight pesticides that are commonly used on leafy greens and/or tomatoes were tested at three concentrations, ranging from the lowest to highest as recommended in their applications.  Each pesticide solution was prepared in sterile distilled water containing ca. 4 log CFU/ml of each pathogen individualy and incubated at 21 °C. The population of each human pathogen in pesticide solution was monitored up to 24 h.

Results: The fungicide/bactericide copper hydroxide (Kocide); and the insecticides Assail, Mustang and Ambush were significantly (P < 0.05) inhibitory to both pathogens in a concentration dependent manner. The fungicide chlorothalonil (Bravo), and the insecticides Beleaf and Intrepid did not show significant effect on both pathogens. However, the fungicide azoxystrobin (Quadris) showed a significant (P < 0.05) stimulatory growth effect only on E. coli O157:H7 after 6 h of incubation at 21 °C.  

Significance: The findings of this study indicate that, depending on the specific pesticide, some may serve as a potential carrier of human pathogens to fresh produce if contaminated water is used in their preparation, whereas others could be an additional barrier to such a contamination event.  This information is critical in risk assessment of food safety of fresh produce.