Preharvest control of zoonoses, food-animal-borne human pathogens, is critical to the safety of meat, poultry, fruits, and vegetables.  Epidemiological and research results in the past decades have demonstrated zoonotic contamination of crops and waterways by food animal facilities, including dairies.  Additional research has shown that despite improvements in slaughter processes over the past two decades, pathogens going into an establishment will emerge on the final product. There are successes in reducing and even eliminating on-farm zoonotic carriage but most of the successes have been for animal pathogens, not human pathogens.  While “farm to fork”, and “gate to plate” has been touted for over a decade, little progress has been accomplished on the farm end.    There are economic, practical and political hurdles to overcome for reducing or eliminating zoonoses on the farm. This round table will include speakers from industry, academia, a regulatory agency and USDA Agriculture Research Service.  The round table will offer a lively discussion of the science, opportunities, need, and hurdles to implementing more effective preharvest control of zoonoses.  IAFP 2015 will be an excellent venue for discussing these issues.