P2-68 Efficacy of Lactic Acid, Hot Water, and Acidified Sodium Chlorite for the Reduction of Non-O157 Shiga Toxin-producing Escherichia coli (STEC) Utilizing a Hot Carcass Model and Escherichia coli O157:H7 as an Indicator

Tuesday, July 30, 2013
Exhibit Hall (Charlotte Convention Center)
Nanditha Jasti, Texas Tech University, Lubbock, TX
W. Evan Chaney, Texas Tech University, Lubbock, TX
Alejandro Echeverry, Texas Tech University, Lubbock, TX
Guy H. Loneragan, Texas Tech University, Lubbock, TX
Kendra Nightingale, Texas Tech University, Lubbock, TX
Mindy M. Brashears, Texas Tech University, Lubbock, TX
Introduction: To address the emergent concern of non-O157 STEC impact on public health, USDA-FSIS regulations recently declared six non-O157 STECs as adulterants in ground beef and non-intact beef products. Testing for individual non-O157 STECs in addition to Escherichia coli O157:H7 may result in substantial increases in production costs for beef producers.

Purpose: To measure reductions of each non-O157 STEC serogroup included as an adulterant by applying lactic acid (LA; 5±0.2%), hot water (HW; 180 ±5° F) and acidified sodium chlorite (ASC; ≤1100 PPM) in parallel with E. coli O157:H7 in a hot carcass model (Brisket).

Methods: Briskets (n=14) were heated to 37°C, cut into halves and four brisket halves randomly assigned to each of seven serogroups (O157:H7, O26, O121, O45, O145, O111, O103). Four per each serogroup, brisket halves were inoculated by submersion into a 3-strain inoculum cocktail for 1 minute, allowed 30-minute bacterial attachment time, followed by simultaneous application of antimicrobial interventions (LA, HW and ASC). Pre-intervention and post-intervention swabs were obtained and plated onto MacConkey agar.

Results: Lactic acid significantly reduced the non-O157 STECs and the reductions are not statistically different compared to E. coli O157:H7, with the exception of STEC O111 (P = 0.049). When treated with HW, a 0.57-log reduction of E. coli O157 was achieved, which is not statistically different from serogroups O26, O121, O145, and O45. This study showed a log reduction of 0.63 for STEC O157 when treated with acidified sodium chlorite, which is significantly not different from serogroups O26, O121, O145, and O45.

Significance: These data indicate E. coli O157 is an effective indicator of intervention efficacy for the non-O157 STEC serogroups O26, O121, O145, and O45 and O103 when 5% LA is utilized, but may not be justified for serogroups O111 and O103 when HW or ASC are utilized.